Fenbendazole (methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl) carbamate) is an animal anthelmintic with a long track record of safety in humans for use against parasites including Ascaris, hookworm, and Trichuris. It is also an established treatment for some hematological disorders such as acute promyelocytic leukemia.

It is believed to work by inhibiting the growth of microtubules, which provide structure to cells. Cancer cells have different microtubules than normal cells and are thus targeted by fenbendazole.

The drug has been shown to destabilize microtubules and cause cell death in laboratory tests using colorectal cancer cells. The researchers found that fenbendazole can induce apoptosis and G2/M cell cycle arrest in the cancer cells by binding to tubulin and disrupting its polymerization. It also induced ferroptosis in the cells, but they did not find evidence that this was the primary mechanism of cell death.

In addition to its cytotoxicity, fenbendazole also prevented the recurrence of colorectal cancer in mice by targeting cancer stem cells. However, the authors of the study concluded that further studies are needed to understand how fenbendazole works in human patients.

A spokesperson for Cancer Research UK told Full Fact that there isn’t enough evidence that fenbendazole can cure cancer. He said that the claim that it does was made by Joe Tippens, who claimed that he took a combination of fenbendazole and supplements to cure his cancer in 2016. However, Tippens hadn’t undergone any clinical trials or had his case reviewed by a medical professional. fenbendazole for humans cancer

Leave a Reply

Your email address will not be published. Required fields are marked *


Explore More

Exploring the Exquisite Blend: The Strawberry Kiwi Strain

January 16, 2024 0 Comments 0 tags

A Burst of Flavor and Aroma The Strawberry Kiwi strain, a hybrid cannabis cultivar, has taken the cannabis community by storm with its captivating combination of flavors and aromas. This

L’Art de la Cuisine au Grill

November 21, 2024 0 Comments 0 tags

Une Méthode de Cuisson Ancienne et AuthentiqueLe grill est une méthode de cuisson qui remonte à des milliers d’années. Traditionnellement utilisée par les civilisations anciennes, il permet de cuire les

Die Lüneburger Umzugsfirma

November 4, 2024 0 Comments 0 tags

Professionelle Umzugsdienstleistungen Die Lüneburger Umzugsfirma ist Ihr kompetenter Partner für einen stressfreien Umzug. Mit langjähriger Erfahrung in der Branche bietet das Unternehmen eine breite Palette von Dienstleistungen an, die auf